Groundbreaking In-Office Blood Typing Products
RapidVet’s blood typing products bring the latest and best thinking to improve the quality of transfusion medicine – and preserve and improve the quality of life for your canine and feline patients.
We’re a trusted partner to thousands of veterinarians, emergency animal clinics, blood banks, and academic institutions worldwide who rely on our blood typing tests to help avoid potentially fatal transfusion mistakes. In fact, we’re the #1 provider of in-office blood typing products in North America– a testament to the quality of our products, backed by our exceptional customer service.
Explore our current product portfolio below to learn about our array of tests that use the proven blood typing technologies available today. Additional feline and canine typing products based on these and evolving testing methodologies are under development.
Dogs can have more than one blood type. And while it’s true that many dogs may tolerate an initial incompatible transfusion because most don’t have naturally occurring antibodies to incompatible blood groups, veterinary best practice – and your patients’ long-term health – dictates that such transfusions be avoided. That’s why RapidVet offers a selection of canine blood typing kits to ensure safe and effective transfusions.
All of our canine blood typing cards are:
RapidVet-H Canine Agglutination Test Cards for DEA 1
Although all dog erythrocyte antigen (DEA) blood types are capable of stimulating the formation of isoantibodies, DEA 1 is considered the most clinically important in causing an acute reaction from transfusion of incompatible blood. That’s because DEA 1 is thought to have the greatest stimulation potential and is considered the primary lytic factor in canine transfusion medicine. In fact, 40% of all dogs are estimated to be DEA 1-positive, and most reactions resulting from the transfusion of incompatible cells occur when blood identified as DEA 1-positive is given to a sensitized DEA 1-negative recipient.
Our canine agglutination test cards provide a fast, simple way to classify dogs as DEA 1-positive or -negative. Like our widely used feline agglutination test cards, these canine products are based on RapidVet’s pioneering point-of-care blood typing methodology.
RapidVet-H Canine Agglutination Test Cards for other Blood Types
Transfusion incompatibility can occur even between dogs that are DEA 1 compatible due to the presence of other blood group antigens in the donor or recipient. Testing for blood types other than DEA 1 provides vital information during pre-transfusion workup and donor selection. RapidVet offers the only in-office tests for canine DAL, DEA 4, and DEA 5.
One of the blood types that can cause both acute and delayed hemolytic transfusion reactions is DAL. While most dogs are DAL-positive, the incidence of DAL varies greatly depending on the breed. Doberman Pinschers are especially at risk since the prevalence of both DAL-negative blood and von Willebrand disease is relatively high. Other breeds reported having a higher occurrence of DAL-negative blood include Dalmatian, Shih Tzu, Lhasa Apso, Bichon Frise, Cane Corso, Pug, Mastiff, and some mixed breeds. DAL typing is particularly important in those breeds and in patients with a history of transfusion, an undocumented history, and those needing multiple transfusions.
Canine DEA 4
While rare, DEA 4 incompatibility does exist. DEA 4 is found to be present in 98% of dogs, and the formation of antibodies against it occurs in the rare instance when DEA 4-positive blood is given to a DEA 4-negative dog. This can have serious consequences in cases of subsequent transfusions, including acute hemolytic transfusion reactions from anti-DEA 4 alloantibodies in sensitized dogs. It has been reported that only 75% of Doberman Pinschers are DEA 4 positive, so typing for DEA 4 prior to transfusion may be of special importance in this breed. DEA 4 typing can help determine the possible cause of an incompatible crossmatch between dogs that are DEA 1-compatible.
Canine DEA 5
DEA 5 antigens are reported to occur on red blood cells in 10% to 25% of the canine population in the United States. In Greyhounds, the prevalence of DEA 5-positive blood has been reported to be as high as 30%. Although not all remaining DEA 5-negative dogs have detectable alloantibodies, an estimated 10% of those dogs have naturally occurring antibodies to DEA 5 antigens. These natural antibodies to DEA 5 antigen have not been reported to cause severe hemolytic reactions; however, incompatible DEA 5 blood is more rapidly hemolyzed within 4-5 days of transfusion and may result in a delayed reaction or contribute to a diminished response to treatment.
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